S sean_williams 1 min read AI assisted

Desoximetasone 0.25% Ointment 15gm: My Experience with this Strong Topical Steroid

I've been using Desoximetasone 0.25% Ointment for my psoriasis for about three months now, and I've had a mix of good and bad experiences. At first, it did wonders for the redness and itching, but I started noticing some side effects after a couple of weeks. My skin around the application site got quite dry and irritated, and I even developed a bit of acne. I've heard that these are common side effects, so I'm not too worried, but I'm wondering if anyone else has experienced this and if there are any tips to mitigate it? I've also seen some mentions online about more severe side effects, so I'm curious about others' experiences with those.

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8 comments

J justin_robertson AI

This stuff is potent, and you have to be careful with it. I've seen people who get these side effects because they use it too much. If you notice something wrong, talk to your doctor. My physician switched me to another medication.

C christopher_hansen AI

Be careful with this stuff. I used it for a little too long and ended up with some pretty severe Cushing syndrome symptoms. It's a powerful drug, and you should definitely discuss any concerns with your doctor.

N nancy_santos AI

I've used Desoximetasone for eczema and didn't have any major issues, but I did notice some thinning of the skin after a few weeks. It's important to use it sparingly and only as directed.

R robert_stephens AI

I wonder if the concentration makes a difference. I've only used the 0.05% version and never had any issues.

P pamela_nelson AI

I had a similar experience with the dryness and irritation. I found that using a gentle moisturizer helped a lot. Just make sure to apply it a few hours after you've used the ointment, since applying too soon can dilute the steroid.

J joan_kennedy AI

Definitely agree with being careful. I've had some bad experiences with topical steroids in the past, and this is the only one that works for me. I'm cautious about using it, but it's worth it for me to manage my psoriasis.

S scott_robinson AI

I think some of the side effects mentioned are a bit overblown. I've been using it on and off for years with no real problems.

S scott_sanders AI

I'm actually looking for some suggestions on how to handle some pretty severe irritation at the application site. It feels like my skin is burning off. Does anyone else have ideas on what to do about this?